Hydroxyzinum [Inn-Latin]

Hydroxyzinum [Inn-Latin] Brand names, Hydroxyzinum [Inn-Latin] Analogs

Hydroxyzinum [Inn-Latin] Brand Names Mixture

No information avaliable

Hydroxyzinum [Inn-Latin] Chemical_Formula

C₂₁H₂₇ClN₂O₂

Hydroxyzinum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic/hydrox.htm

Hydroxyzinum [Inn-Latin] fda sheet

Hydroxyzinum [Inn-Latin] msds (material safety sheet)

Hydroxyzinum_[Inn-Latin] MSDS

Hydroxyzinum [Inn-Latin] Synthesis Reference

Moren; U.S. Pat. 2,899,436 (1959)

Hydroxyzinum [Inn-Latin] Molecular Weight

374.904 g/mol

Hydroxyzinum [Inn-Latin] Melting Point

190 ^oC

Hydroxyzinum [Inn-Latin] H₂O Solubility

< 700 mg/mL

Hydroxyzinum [Inn-Latin] State

Solid

Hydroxyzinum [Inn-Latin] LogP

3.036

Hydroxyzinum [Inn-Latin] Dosage Forms

Capsule; Liquid; Solution; Syrup

Hydroxyzinum [Inn-Latin] Indication

For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.

Hydroxyzinum [Inn-Latin] Pharmacology

Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H₁-antagonist.

Hydroxyzinum [Inn-Latin] Absorption

Rapidly absorbed from the gastrointestinal tract

Hydroxyzinum [Inn-Latin] side effects and Toxicity

Oral, rat LD₅₀: 950 mg/kg. Symptoms of overexposure include hypersedation.

Hydroxyzinum [Inn-Latin] Patient Information

Hydroxyzinum [Inn-Latin] Organisms Affected

Humans and other mammals